Solid Dosage Production Line

The Solid Dosage Granulation Line from NOAH is a comprehensive solution for wet granulation, drying, and calibration processes in pharmaceutical manufacturing. This line integrates various machines such as High Shear Granulator, Fluidized Bed Dryer, Conical and Cylindrical Calibrators, and others to ensure efficient and contamination-free production.

Here's a detailed breakdown of the components and processes involved in this line:

High Shear Granulator: This machine is used for mixing and granulating raw materials. It combines dust particles to form granules within specified limits. Wet granulation improves the flow properties, homogeneity, and compressibility of the powder mix.

Fluidized Bed Dryer: This dryer is used to reduce the moisture content of powder and granules. Hot air is passed through a perforated bed of moist solid particles, lifting and suspending them in a stream of air. Heat is transferred by direct contact between the wet solid and hot gases, vaporizing the liquid and carrying it away with the drying gases.

Conical and Cylindrical Calibrators: These calibrators are used for sizing and shaping the granules to ensure uniform particle size.

Vacuum Conveying Device and Lifting Turnover Discharging System: These systems greatly decrease labor intensity and avoid dust pollution, saving on labor costs.

PLC Control System: The entire line is controlled by an automatic PLC system with a graphical interface. This allows for automatic setting of operation and process parameters, as well as history review and printing.

CIP System: The Cleaning-In-Place (CIP) system ensures effective cleaning of the granulator and dryer, maintaining hygiene and preventing cross-contamination.

Ex-Proof System, Reliable Interlock, and Earthing: These safety features ensure the safety of people, equipment, and the environment.

The Solid Dosage Granulation Line is available in capacities ranging from 45L to 1500L and can carry out two different processes: 

Wet granulation and drying. NOAH offers customization options, designing and sizing granulation lines according to specific process and specification requirements.

This line is suitable for the pharmaceutical, food, and chemical industries. NOAH provides comprehensive services, from project initial design and confirmation to detailed design, equipment selection, and installation. They are a reliable and reputable manufacturer of solid dosing granulation lines in China, offering advanced technology and support for customers' production lines.

In conclusion, the Solid Dosage Granulation Line from NOAH is a comprehensive and efficient solution for wet granulation, drying, and calibration processes in pharmaceutical manufacturing. With its integration of various machines, automation, and safety features, it ensures efficient, contamination-free, and safe production.

1. High Shear Mixer Granulator

Purpose: To optimize the wet granulation process by turning a heterogeneous powder mixture into uniform, high-density granules with proper flow and compactness.

Operation: Powder material can be manually added or sucked into the high-speed mixer by a vacuum feeder. Liquid is added via a pump (optional) while the mixer operates according to a set program.

2. Wet Granulator / Wet Conical Mill

Purpose: To further process the wet powder from the high shear granulator into uniform wet granules.

Operation: Wet powder is discharged into the wet granulator, which uses a conical mill mechanism to produce uniform wet granules.

3. Fluid Bed Dryer / Fluid Bed Granulator

Purpose: To dry the wet granules and remove moisture.

Operation: Wet granules are transported to the fluid bed dryer using negative pressure and process air. Hot air is introduced to lift and suspend the wet solids in a fluidized state, enabling heat transfer and moisture removal.

4. Lifting Column / Hopper Elevator

Purpose: To enhance efficiency and mobility in material handling.

Operation: Lifts materials, such as dried granules, and discharges them directly into a powder blender or vibration sieve.

5. Conical Mill

Purpose: To sieve agglomerates from granulators and obtain evenly qualified granules.

Features: Easy to operate and clean, fully compliant with GMP.

6. Other Machinery

Options: Based on material characteristics and customer requirements, the line can be equipped with a vacuum conveyor, powder screening machine, and powder mixer.

7. Documentation

Purpose: To facilitate training, operation, and maintenance of the equipment throughout its lifecycle.

Content: NOAH provides a complete set of GMP documentation, including DQ, IQ, OQ, SAT, FAT, and user manuals.

Business Opportunities

For those interested in starting a pharmaceutical granulation production line business, NOAH offers detailed specifications, quotations, and layout drawings upon request.

In summary, the solid oral dosage granulator line is a comprehensive system that includes key machinery for mixing, granulating, drying, and handling materials. NOAH provides customized documentation and support to ensure efficient and compliant operation of the equipment.

Continuous processes are more autonomous. And multiple processes can be carried out with the same equipment. It means that several processes such as loading, granulating, drying, coating, and sizing are carried out in the fluid bed granulator. Granulating, wet cone mill, drying, coating, lifting,transferring, dry cone mill, blending in the same solid preparation granulator lines.

This solid preparation granulator lines for a product factory, one high shear mixer granulation machine with one fluid bed processor, and one custom combine pharma lifter and vacuum conveying with a cone mill.

Services

Pre-sales and After-sales Services: Assist customers in acquiring and using granulation processing equipment.

Maintenance and Troubleshooting: Engineers offer assistance during regular equipment maintenance, provide fluid bed granulation troubleshooting, and handle on-site repairs.

Training: Offer training for operators to maximize factory efficiency.

Contact Information

Contact Page: Send a request on NOAH machinery's contact page.

Email: chnoah@noah-pm.com

Mobile & whatsapp: +86 15161878967